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Abstract Vitamin D plays an essential role in calcium homeostasis and bone metabolism. Recent evidence suggests that vitamin D may also be important for a variety of non-skeletal outcomes including neuromuscular function, immunomodulation, and control of other hormonal system. It is well known that exposure of skin to direct sunlight is the most important source of vitamin D, so that according to many causes like fear of skin cancer, traditional clothing and spending most of the time indoors many Egyptian girls are exposed to vitamin D deficiency. Hypovitaminosis D is a widespread disorder in developing countries across all age groups, regardless of their latitude. Clinical manifestations of hypovitaminosis D are not limited to musculoskeletal disorders, but may also include an increased risk of respiratory infections, diabetes mellitus and possibly cardiovascular diseases The aim of this study was to evaluate the magnitude of vitamin D deficiency/sufficiency in a sample of Egyptian boys children. The present study was conducted on 80 boys age from (2-10) years old randomly selected from outpatient clinic of Ain Shams University and their healthy relative. We excluded girls, boys whose age<2 years or >10 years, boys suffering from chronic illness or on drugs as corticosteroid and anti-epileptic drugs. For all subjects the following was performed: 1. History taking with special emphasis on dietary habits, social status, housing condition, and sun exposure 2. Physical examination including anthropometric measurement (weight, height, BMI) and search for any skeletal deformity. 3. The following laboratory tests were performed: 25(OH) D by ELISA Serum calcium. Serum phosphorus Serum albumin Serum alkaline phosphatase Hemoglobin concentration. Conclusion This study showed high prevalence of vitamin D deficiency among Egyptian boys age (2-10 years old) due to decrease sun exposure time. |