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Abstract Objectives: To evaluate the diagnostic performance of dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) for the characterization of complex ovarian tumors, by using histologic findings as the reference standard. Patients & methods: 25 patient (age range from 23 to 61) with complex ovarian masses underwent DCE-MRI before surgical excision. The study included 8 benign, 3 borderline & 14 malignant masses. The following kinetic parameters were analyzed: enhancement amplitude (EA) in the form of MRE%, time to peak in the form of T max & maximal slope (MS) & correlated with histopathological results. Results: DCE-MRI achieved higher overall accuracy (88%) & specificity (87.5%) than conventional MRI. MRE% was higher for malignant than for benign (p0.001) & borderline masses (p0.002). T max was of shorter duration in malignant than in benign (p, < 0.001) and borderline (p, 0.019) masses. MS was the best criterion to differentiate between benign, borderline & malignant tumors. Type III curve was specific for invasive malignant tumors. Conclusion: DCE-MRI can be a useful tool in characterization of complex ovarian masses & in differentiating between borderline & invasive malignant neoplasms. |