الفهرس 
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Abstract
The present study was carried out in the farm of Faculty of Veterinary Medicine, Suez Canal University, and in El-Slahia farm, Ismailia, Egypt .The total number of animals used in this investigation were130calves (53 buffalocalves and77 Frisian calves).
Blood with and without anticoagulant and fecal samples were collected from diseased and control groups. Heparinized blood was used for complete blood picture. Serum samples were used for biochemical analysis of sodium, potassium, chloride, total proteins, albumin and globulins. Protein electrophoresis was calculated to detect the level of each protein fraction. Fecal samples were used to detect the presence of parasitic infestation.
The study revealed that the clinical signs of infected calves showed mild to severe diarrhea, few cases of dehydration.The haematologicalfindings showednon significant variations in hemoglobin and leukocyte but RBCs showed a significant decrease in mild cases of diarrheic calves and PCV showed highly significant increase in severe groups in both farms. Biochemical analysis of serum showed non significant differences in sodium and potassium, while chloride showed highly significant increase in severe group of the 1st farm. Total proteins showed a significant increase in severe group of the 1st farm, while albumin showed a significant increase in severe group of El-salhya farm but globulin showed a significant increase in all groups of diseased calves of the faculty farm. Protein electrophoresis revealed that only α1 globulins showed highly significant increase in diseased calves.