الفهرس 
Introduction and Aim of the WorkOnly 14 pages are availabe for public view
 |  | from | 159 |  |  |
| | | from | 159 | | |
Abstract
The aim of this study was to investigate the correlation of Helicobacter pylori infection and atrophic gastritis status on the risk of metabolic syndrome.
This was a Prospective cross sectional study conducted on 34 patients of metabolic syndrome. Age ranges between 22 to 64 years old; 21 male and 13 females, recruited from endoscopic unit at Minia university hospital from April 2017 to April 2018.
Patients included in our study were subdivided into 2 groups: group 1 Included 34 patients with metabolic syndrome. Age ranges between 22 to 64years old; 21 male and 13 females and group 2 Included 26 patients (14 male and 12 females) not fulfilling criteria of metabolic syndrome
All participants included in our study were subjected to careful history taking, full clinical examination, laboratory studies included (Fasting blood glucose level, Hemoglobin A1C, Serum urea & creatinine, Lipid profile and measurement of HP-specific IgG concentration) and gastric mucosal biopsy.
Serum H.pylori IgG level was significantly higher in cases of atrophic gastritis with p- value <0.001 when compared with non-atrophic gastritis.
H. pylori IgG level has moderate positive correlation with DBP, LDL level and triglyceride level r is 0.518, 0.709 &0.535 respectively and fair positive correlation with BMI, SBP and HbA1c r is 0.482, 0.474 & 0.468 respectively
Atrophic gastritis has moderate positive correlation with SBP and DBP r is 0.523 and 0.501 respectively and fair positive correlation with LDL level and triglyceride level r is 0.475 & 0.306 respectively.
By using linear regression analysis for studying the effect of H. pylori infection and atrophic gastritis on the risk of metabolic syndrome, there was no significant association have been detected, On the other hand, atrophic gastritis was significant risk of metabolic syndrome.
from our study we can concluded that:
The study showed that Serum H.pylori IgG level was significantly higher in cases of atrophic gastritis with p- value <0.001 when compared with non-atrophic gastritis.
Atrophic gastritis was significant risk of metabolic syndrome.