الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Thrombocytopenia is the most common coagulation disorder seen in the ICU patients and has been shown to be associated with longer ICU stays, a higher incidence of bleeding events, greater transfusion requirements, and higher mortality.This prospective observational study analyzed data collected from 50 adult (age ≥ 18 years) patients with multiorgan failure (defined as SOFA score of ≥ 3 in ≥ 2 organ systems) admitted to critical care medicine department at Benha University over a period of 12 months. They were classified into 2 groups; group I and group II. group I included 30 patients with thrombocytopenia (defined as a platelet count <150,000/μl) on admission or developed it anytime during the ICU stay, and was divided into: group A; thrombocytopenic patients who remained thrombocytopenic till end of study, and group B; thrombocytopenic patients who became non thrombocytopenic at end of study. group II included 20 patients without thrombocytopenia during the ICU stay.All included patients were evaluated till discharge from the ICU by major bleeding events (life-threatening or compromising hemodynamic status), transfusion requirments, length of ICU stay, need for organ supportive measures (vasopressors, mechanical ventilation or hemodialysis), SOFA score and survival.