الفهرس 
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Abstract
oronary artery disease is most commonly due to atherosclerotic occlusion of the coronary arteries. It is estimated that if all forms of major CVD were eliminated, life expectancy would rise by almost 7 years.
Coronary heart disease (CHD), in particular, has a long asymptomatic latent period that provides an opportunity for early preventive interventions.
The Framingham Heart Study has helped to elucidate major risk factors for CVD. Furthermore, through its various multivariate risk scores it has helped to identify those at highest risk for developing CVD. These screening tools have been replicated in other developed country cohorts and contribute to the screening and management of those at high risk of CVD.
In the current study we aimed at evaluating the correlation between the cardiovascular risk assessed by Framingham score and the extent of atherosclerotic cad affection among patients assessed by MDCT due to chest pain complaints.
The study included 100 patients: aged from 30 to 79 years old, of which 63 % were males, 63 % were hypertensive, 39 % were diabetic, 28 % were smokers and who presented with symptoms suggestive of coronary artery disease (chest pain).all patients were subjected to history and examination, ECG, kidney functions, lipid profile, FRS calculation and coronary MDCT scan.
FRS allowed classifying them into three groups: low risk FRS group (FRS score < 10), intermediate risk FRS group (FRS score 10: 20) and high FRS group (FRS >20).
MDCT scan allowed evaluating the presence or absence, site, significance of stenosis and number of atherosclerotic lesions, more over it allowed their classification according to CACS (no calcification group, mild calcification group, moderate calcification group and severe calcification group).
The study showed that there is statistically significant positive correlation between FRS & CAD, having a higher FRS category carries a higher probability of having higher risk CAD.
Also there is positive correlation between Framingham risk category and calcium score grading. But there is a weak correlation between FRS category and number of diseased coronaries i.e. FRS cannot differentiate single vessel disease from MVD.