الفهرس 
Primary Open Angle Glaucoma
DiagnosisOnly 14 pages are availabe for public view
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Abstract
G
laucoma is the leading cause of irreversible blindness in the world. Primary open angle glaucoma is the most common type of glaucoma.
In this observational, cross-sectional study, we will address the key to important question; is there a relationship between the functional loss in the sensitivity to light and the structural loss of retinal ganglion cell axons?
So, we examined the relationship between the most common functional test, the 24-2 standard automated perimetry visual field, and structural tests of retinal nerve fiber layer thickness measured with optical coherence tomography.
All participants underwent intra ocular pressure measurement, visual field testing by Humphrey field analyzer, fundus photography and optical coherence tomography.
In this study, A total of 30 eyes with primary open angle glaucoma were included. Average age of the patients included in the study is 56.7±15.9 years. Majority were female patients constituting 60% of the study population.
In this study we found that, there is a statistically significant negative correlation between mean deviation and average retinal nerve fiber layer thickness, and a statistically significant negative correlation between pattern standard deviation and average retinal nerve fiber layer thickness.
It was found that there are statistically significant positive correlations between average retinal sensitivity of the superior hemifield and average retinal nerve fiber layer thickness as well as inferior optical coherence tomography retinal nerve fiber layer thickness.
Also, we found that there are statistically significant positive correlations between average retinal sensitivity of the inferior hemifield and average retinal nerve fiber layer thickness as well as superior optical coherence tomography retinal nerve fiber layer thickness.
In this study we found that there is a statistically significant positive correlation between intra ocular pressure and vertical cup to disc ratio.
A statistically significant negative correlation was found between vertical cup to disc ratio and average retinal nerve fiber layer.
In this study we found that there are statistically significant positive correlations, between vertical cup to disc ratio and (mean deviation and pattern standard deviation) of visual field.