الفهرس 
Diabetic Foot UlcerOnly 14 pages are availabe for public view
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Abstract
Diabetic foot ulcer can be treated be debridement, appropriate antibiotic, non-weight bearing and vascular surgery. In addition, there are many new techniques for treatment of diabetic foot ulcers as bioengineered tissue, platelet derived growth factor and the use of hyperbaric oxygen therapy and the use of ozone therapy.
Because Ozone (O3) is a strong anti-oxidant; it can exert protective effects on DFU by oxidative preconditioning, stimulating and/or preserving the endogenous antioxidant systems and by blocking the reactive oxygen species generation.
Ozone has been used with good results in treatment of patients with diabetic foot, because of its germicidal properties and its influence on the processes of oxygen metabolism and other effects.
This was a prospective cross-sectional study conducted on 50 patients of diabetic foot ulcer at Menoufia University Hospital and Moustafa Kamel Military Hospital out of consecutive patients from April 2017 with diabetic foot ulcer received Ozone therapy in pain management unit. Patient’s selection based on clinical diagnosis, laboratory investigations, plain X-ray and Duplex Ultrasounds.
Patients received 2 sets of local Ozone therapy weekly for 10 weeks, evaluated for degree of healing and followed up for 8 weeks after the end of therapy for recurrence.
This is cross sectional prospective study of cases of diabetic foot ulcer admitted to the surgical department. There was no difference in groups regarding age and sex, type of diabetes, the length of previous treatment
Statistical analysis revealed a significant reduction in the length and width of the ulcer in all groups. Most of our patients showed complete healing (70%) and 26% showed partial healing while only 4% showed non-healing.
Only 11.4% of cases of complete healing showed recurrence and the statistical analysis revealed that the use of ozone therapy markedly improve healing of DFU with low incidence of recurrence and decreased drugs used during the period of therapy significantly.
from our study we can summarize that: the use of local ozone therapy in cases of diabetic foot ulcers help to fast healing process by a good degree.