الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
This is an observational case-control study that aimed primarily to assess the safety and efficacy of an accelerated dobutamine stress echocardiography protocol in the evaluation of coronary artery disease compared to the conventional protocol. Eighty consecutive patients who were presenting for a clinically indicated diagnostic DSE (with intermediate PTP to CAD) have been prospectively enrolled in the study at national heart institute. They were randomly assigned to undergo either the accelerated (group A, 40 patients) or the standard DSE protocol (group B, 40 patients) from June 2018 to January 2019.Patients with any of the following were excluded: myocardial infarction within 3 days, unstable angina, recent ventricular tachycardia, severe hypertension, significant aortic stenosis, and uncontrolled atrial fibrillation. A complete history was taken from the patients including all risk factors. For each patient, 2-dimensional echocardiographic images were recorded at baseline, low dose, peak stress, and during recovery along with continuous monitoring of ECG and hemodynamics.Off-line assessment of echocardiographic images was done by an investigator who is blinded to clinical information, electrocardiographic findings, and study protocol. Assessment of Regional wall motion grading was according to the recommendations of the American Society of Echocardiography using a 17-segment mode.We compared the different demographic data, risk factors, drug history, hemodynamic data, DSE test results, and echocardiographic parameters among groups.