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العنوان
FETAL HEMOGLOBIN IN MATERNAL SERUM AS A PREDICTOR OF SEVERE PREECLAMPSIA /
المؤلف
Abd EL ALL, Kareem Mohamed Kamal.
هيئة الاعداد
باحث / كريم محمد كمال عبدالعال
مشرف / نجوى ابراهيم السعيد محمد عجلان
مشرف / وسام صلاح محمد ابراهيمم
مشرف / محمد احمد طلعت الشعراوى
الموضوع
Obstetrics and Gynecology.
تاريخ النشر
2019.
عدد الصفحات
p 63. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض النساء والتوليد
تاريخ الإجازة
21/8/2019
مكان الإجازة
جامعة طنطا - كلية الطب - امراض النساء والتوليد
الفهرس
Only 14 pages are availabe for public view

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Abstract

SUMMARY
Introduction: About 10% of pregnancies are complicated by hypertension. Preeclampsia accounts for 70% of hypertension in pregnancy. preeclampsia is a disease associated with high maternal and perinatal morbidity and mortality. Fetal hemoglobin is structurally made up of 2 alpha and 2 non-alpha chains; in addition, Hb-F has 2 - gamma chains and the predominant adult blood HbA1 has 2 beta chains.
Aim of the work: The aim of the study was to assess the role of measuring free fetal haemoglobin of maternal serum as a predictor of severe preeclampsia in cases of mild preeclampsia
patients & Methods: The study included fifty pregnant women admitted to tanta University Hospital.
50 cases presented with signs and symptoms of mild preeclampsia
as follows :Arterial blood pressure ≥ 140/90 mm Hg and < 160/110 mm Hg (measured 2 times at least 6 hours apart and less than 1 week) and proteinuria: ≥ 0.3g & < 5.0 g/24 hours or 2+ on dipstick analysis of midstream or catheter urine
Methods: after history, examination & ultrasound assessment of fetal condition 5 ml of maternal venous blood were collected & Free fetal hemoglobin (Hb-F) was differentiated from the adult form (Hb-A) by Human fetal Hemoglobin ELISA Quantitation Set.
Results: The study is comparative study which there was statistical significant higher level of free fetal hemoglobin in cases of severe preeclampsia terminated before 34 weeks more than cases terminated after 34 weeks including mild preeclampsia and severe