الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 92 |  |  |
| | | from | 92 | | |
Abstract
Hair is considered as one of the most defining aspects of human appearance. hair loss is a common and distressing problem that has a significant impact on quality of life. It is often met with feelings of grief, loss of self confidence, and low self-esteem. Physicians should not underestimate the emotional effects of hair loss. About 40% of patients felt dissatisfied with the way in which their doctor dealt with them.
Telogen effluvium (TE) is the most common form of hair loss. It is caused by any disruption of hair growth cycle resulting in increased synchronized telogen hair shedding. chronic TE (CTE) is a primary or idiopathic generalized shedding of telogen hairs from the scalp lasting more than 6 months without any apparent cause.
Vitamin D deficiency may cause CTE, and its supplementation may terminate the disorder. There is an opposing argument that there exists no relationship between vitaminD and CTE so far.
Reports have been published on oral vitamin D supplementation with encouraging results for cases of CTE. .
Vitamin D have a role in important functional activities within the hair follicle. Further, vitamin D accelerates hair follicle recovery and is a potent inhibitor of hair follicle regression that is associated with hair shedding.
In spite of the fact that studies were done on the effect of VD and VDR in CTE, definite results were not obtained. Therefore, in this study, we evaluated the correlation of VD and VDR in CTE in females.
The aim of the current study was to correlate the relation of VD and VDR in CTE in females, we compared serum levels of VD and tissue expression of VDR in 30 females patients with a CTE and 30 apparently healthy subjects served as a control.
There was significant difference between the patients and control groups in the mean serum VD level (p = 0.0001) and tissue VDR(p=0. 0001).
The mean age of the patient group was 33.9±10.8 compared to 35.8±10.9 years in the control group. There was non significant difference between the patients and control groups regarding age (p = 0.134).
There was a statistically significant Negative moderate correlation
(r=-0.71, p=0.0001) between serum VD and CTE patients included in the study.
There was a statistically significant Negative moderate correlation
(r=-0.64, p=0.0001) between tissue VDR and CTE patients included in the study.