الفهرس 
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Abstract
SUMMARY
B
reast cancer is the most common cancer in women throughout the world. Breast conserving surgery and radiotherapy have been shown to provide similar local control and survival rates to radical procedures in the surgical treatment of early breast cancer.
In this study we compared CBS with MRM regarding oncologic and cosmetic outcomes in women with primary breast cancer negative for estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 (triple-negative breast cancer.
The study was conducted on 20 patients, 10 patients treated with MRM and 10 patients treated with CBS.
Their age ranged between 41-65 years in CBS group compared with 45-70 years.
Patients were included if matched the following criteria:
Patients with proven histopathology of early (stage I-II) breast cancer.
Triple negative patients (Estrogen receptor, Progesteron receptor and Human epidermoidal growth factor receptor 2 HER2).
No other lesions in the same or contalateral breast.
Exclusion criteria:
Patients were excluded if they had any of the following criteria:
Patient with advanced breast cancer.
Patents who are medically unfit for surgery.
Patient with past history of breast cancer.
Patients with contraindication of CBS or radiation.
Patients were included if they agreed to be included in the study and an informed consent was taken.
Workup plan (methodology):
Each patient was subjected to the following:
1- Comprehensive medical history taking and careful clinical examination.
2- Laboratory investigations:
3- Imaging:
4- Diagnostic pathology:
5- Maximal surgical effort:
In CBS, the tumor with adequate safety margin as well as axillary L.Ns. were removed.
In MRM, the whole breast, pectoral fascia and axillary L.Ns. were removed.
6- Post operative:
Cosmetic outcome
Post operative follow up: after 6 months by U\S, sonomammography, or other radiology.
Recurrence.
In conclusion, BCS displayed elevated OS in TNBC patients compared to mastectomy, at least equally. Although cosmetic impairments resulting from mastectomy can be addressed with immediate reconstruction, we still should consider the benefits of improved outcomes and an avoidable deterioration in quality life during the surgical decision-making process. Therefore, BCS is a preferable choice for TNBC patients if given adequate adjuvant treatment.