الفهرس | Only 14 pages are availabe for public view |
Abstract Primary brain tumors are a varied group of benign and malignant tumors originating from the brain parenchyma and its coverings. These lesions are an important cause of morbidity and mortality in both adults and pediatrics, often resulting in severe disabilities and producing high burden in both families and health care systems. The world age-standardized incidence rate for all brain tumors ranged from 4.3 to 18.6 per 100 000 per year. Accurate diagnosis of the brain tumors helps in proper treatment and better prognosis. Perfusion MRI techniques non-invasively estimate the functional hemodynamic parameters. There are many different techniques are available: arterial spin-labeled (ASL), dynamic susceptibility contrast (DSC) and dynamic contrast-enhanced (DCE) T1-weighted perfusion imaging. DSC perfusion is the most studied and widely applied, while ASL, which does not require intravenous contrast, has been the subject of increasing investigation and clinical implementation. The aim of our study is to compare between DSC and ASL proving the ability of ASL to be widely applied in neurologic and psychiatric disorders. ASL is a relatively new technique depends on an endogenous tracer unlike DSC which uses exogenous gadolinium-based contrast agent. So ASL is superior to DSC for patients with renal failure and for those who need repeated follow-ups. |