Search In this Thesis
   Search In this Thesis  
العنوان
The relation between blood cell indices and the severity of coronary artery diseases (CAD) before and after primary percutaneous coronary intervention (PCI) /
المؤلف
El-Shimy, Ahmed Adel.
هيئة الاعداد
باحث / أحمد عادل الشيمي
مشرف / طارق السيد جودة
مشرف / صلاح الشحات عارف
مشرف / محمد صلاح احمد
الموضوع
Coronary Artery Diseases. Primary percutaneous coronary. Blood cell - Coronary.
تاريخ النشر
2019.
عدد الصفحات
online resource (108 pages) :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب الباطني
تاريخ الإجازة
1/1/2019
مكان الإجازة
جامعة المنصورة - كلية الطب - الباطنة العامة – الحالات الحرجة
الفهرس
Only 14 pages are availabe for public view

from 132

from 132

Abstract

Introduction: Many studies have discussed the relation between CBC parameters and the severity of many diseases. A lot of papers have been published regarding the predictive value of CBC parameters and for risk stratification of ACS patients. An elevated level of mean platelet volume (MPV), a platelet activation marker, has been proven to be useful in detecting a cardiovascular event (CVE). In addition, neutrophil lymphocyte ratio (N/L) was found to be a predictor of MACE in STEMI patients undergoing primary PCI. Also, The significance of RDW as a predictor of long-term Major Adverse Cardiovascular Events (MACE) in STEMI patients undergoing primary PCI was proven Aim of the work: We aim to explore the relation between blood cell indices and development of short-term Major adverse cardiovascular events (MACE) in ST- elevation myocardial infarction (STEMI) patients undergoing Primary PCI. Patient and methods: This study includes 50 patients with STEMI. They were diagnosed by history taking, clinical examination, ECG, ECHO and elevated cardiac enzymes. Blood samples were drawn from those patients and blood cell indices (RDW, MPV, N/L ratio) were recorded. Revascularization for all our patients was done by primary PCI. Follow-up data was collected from our patients within 30-day post primary PCI. Our follow-up data included major adverse cardiovascular events Results: Among the 50 patients selected for our study, 12 patients (24%) developed major adverse cardiovascular events (MACE) within 30 days follow-up. Consequently, we classified our patients into MACE positive and MACE negative patients. RDW, MPV and N/L ratio were significantly higher in MACE positive group. Conclusion: Red cell distribution width (RDW), mean platelet volume (MPV), Neutrophil lymphocyte ratio (N/L) were found to be independent predictors of short term MACE in STEMI patients undergoing primary PCI.