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العنوان
Efficacy of Dietary Calcium and Vitamin D
Supplementation on Rats with Induced Cerebral
Palsy /
المؤلف
Osman, Fatma Naser Ahmed.
هيئة الاعداد
باحث / Fatma Naser Ahmed Osman
مشرف / Hoda Salama IbrahimHoda Salama Ibrahim
مشرف / Naeem Mohamed Rabeh
مشرف / Naeem Mohamed Rabeh
الموضوع
Nutrition and Food Science. Home Economics.
تاريخ النشر
2019.
عدد الصفحات
p. 117 :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Multidisciplinary تعددية التخصصات
تاريخ الإجازة
1/2/2019
مكان الإجازة
جامعة حلوان - كلية الاقتصاد المنزلي - Nutrition and Food Science
الفهرس
Only 14 pages are availabe for public view

from 169

from 169

Abstract

Cerebral palsy is characterized by motor impairment and can present with global physical and mental dysfunction. The aim of the present study was to investigate the effect of dietary calcium and vitamin D supplementation on rats with induced cerebral palsy. Forty five adult male albino rats weighing 180±5gm were divided into 8 groups .The 1st group (n=6) was fed on the basal diet (-ve control). The 2nd to ihgroups of rats (n=39) were injected with 15 ul of ethanol to induce cerebral palsy (CP) and daily ingestion of 20 mg/kg.b.w of sodium phenytoin. The 2nd group of rats continues feeding on basal diet (+ve control). group 3 was fed on daily basal diet supplemented with vitamin D3 by concentration of 15 mcg/ kg/b.w. Groups 4-5 were fed on basal diet supplemented with 40 mg &120 mg of calcium phosphate (level I and 2), respectively. group 6 was fed on basal diet supplemented with level 1 Ca with vitamin D supplementation, while group 7 was fed on basal diet supplemented with level 2 Ca with vitamin D supplementation. At the end of the experimental period (10 weeks), rats were scarified. Results indicated that ethanol CP rats showed a significant P <0.05 decrease in serum vit.D and calcium compared to the negative control one as well as bone minerals density. It was also indicated that supplemented diet with vitamin D and calcium at the highest level (group 7) improved BWG% as well as serum vitamin D and calcium, Also these supplementation increased the bone mineral density compared to the positive control group. We concluded that Vit.D and Ca supplementation had beneficial effects on CP rats.