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العنوان
Role of Glycolipid Immunoglobulin G Antibody Assay in Diagnosis of Pulmonary Tuberculosis /
المؤلف
El-Mallah, Wessam Abdelkader.
هيئة الاعداد
باحث / وسام عبد القادر حسينى الملاح
مشرف / أمل أمين عبد العزيز
مشرف / جيهان على عبد العال
مشرف / بلال عبد المحسن منتصر
الموضوع
Tuberculosis. Chest - Diseases. Pulmonary Disease, chronic Obstructive - therapy.
تاريخ النشر
2019.
عدد الصفحات
108 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب (متفرقات)
الناشر
تاريخ الإجازة
22/12/2019
مكان الإجازة
جامعة المنوفية - كلية الطب - أمراض الصدر والتدرن
الفهرس
Only 14 pages are availabe for public view

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Abstract

This study was carried out on75 Subjects referred to Damnhour Chest Hospital in the period from March 2017 to March 2018.
They were divided into 3 groups:
group I: included 25 patients with active pulmonary TB.
group II: included 25 patients with respiratory disease other than TB.
group III: included 25age and sex matched healthy individuals as the control group.
After having an informed consent; each patient underwent
1. Detailed history taking:
2. Clinical examination:
A thorough general and local chest examination were done.
3. Investigations:
Full routine laboratory investigation in the form of:
 Complete blood picture (CBC).
 Erythrocyte sedimentation rate (ESR) in 1st hour.
 Liver functions (AST&ALT).
 Kidney functions (urea &creatinine).
 Plain chest X-ray (postero anterior & lateral views).
 Sputum smears examination for acid fast bacilli.
Serum level of ATBGL IgG:
The TBGL antibody was measured by ELISA kit by imunoenzymometric assay (ELISA), the measuring unit is U/ml.
Summary
86
The groups were matched regarding age & gender.
There was no statistically significant difference between the studied groups regarding smoking history.
No statistically significant difference was observed between the groups regarding WBCS count.
In our study ATBGL IgG level in group1 ranged between 13.20-20.10 , in group II it ranged between 3-5 while in group III (control group) it ranged between 0.60-1.20. Statistically significant difference was observed regarding ATBGL IgG level and it was elevated in group1 than group II than control group.
ESR level (1st hour) was higher in group I than group II and group III.
Moderate advanced lesions were the commonest in group1, whereas minimal advanced lesions were the least common. In this study TB group ”group I” apical infiltration is the commonest finding, followed by lung cavitation and bronchopneumonia while the least finding was pleural effusion. Whereas group II included lobar pneumonia which was the commonest followed by copd, plural effusion and the least were bronchiectasis, lung abscess and interstitial lung disease.
The level of ATBGL IgG was elevated in pneumonia in group II.
There was significant relation between ATBGL IgG level and smoking history while there was non-significant relation between ATBGL IgG level and gender.