الفهرس 
History and taxonomyOnly 14 pages are availabe for public view
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Abstract
Acinetobacter species are considered challenging pathogens responsible for serious opportunistic infections. Due to their adhesiveness to epithelial cells, they colonize skin, mucous membranes and upper respiratory airway causing a wide range of infections including nosocomial pneumonia, ventilator-associated
pneumonia, septicemia, wound sepsis, urinary tract infection, endocarditis and meningitis.
The aim of this work was to isolate Acinetobacter spp. from patients admitted to the Menoufia University Hospitals, determine antibiotic susceptibility patterns of the isolated spp. with detection of Acinetobacter producing ESβLs and carbapenemases, detection of biofilm-producing Acinetobacter strains phenotypically and genotypically (FimH and CsgA genes), and also assessment of the relation-ship between the ability of biofilm production and antimicrobial drug resistance.
This study was performed in Medical Microbiology and Immunology Department, Faculty of medicine, Menoufia University from May 2018 to April 2019. Two Hundred and Thirty clinical samples were collected and processed according to standard microbiological methods. Acinetobacter species were identified using Vitek -2 system.
A total of 50 Acinetobacter isolates were obtained from different clinical samples. Acinetobacter infections were more common in males (62 %) aged from 30-60 years (48%), who stayed in hospital for more than 7 days (88%), used chemotherapeutic agents (94%), exposed to invasive procedures (86%) and had associated co-morbidities (90%). the highest isolation of Acinetobacter isolates was from ICUs (54%) The highest rate of Acinetobacter isolates was from respiratory samples (48%). Vitek-2 system showed that A. baumannii complex was the predominant Acinetobacter spp. (80%).