الفهرس | Only 14 pages are availabe for public view |
Abstract Summary and conclusion Diffusion weighted image (DWI) provides a non-invasive tool for more accurate diagnosis and staging of urinary bladder cancer. This modality is highly recommended nowadays in staging of known malignancies, differentiating benign from malignant lesions and postoperative scarring from recurrence of the disease. DWI can be helpful in cases when the use of intravenous contrast medium is contraindicated. Also, DWI provides important information about the degree of cellularity in studied tissues which is contributed to the determination of the tumor’s histopathologic grade. Our research showed the ability of DWI to differentiate between different histologic grades and revealed that there is an inversely proportional relationship between ADC value and the tumor’s grade. The main outcome parameters: Sensitivity, Specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy of MRI in pre-operative staging of urinary bladder cancer using T2WI plus diffusion weighted image were 95.65%, 57.14%, 88%, 80%, 86.7% respectively compared to T2WI alone which has Sensitivity, Specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy as 83%, 62%, 83%, 66.7%, 74.5% respectively. In conclusion, adding diffusion-weighted image to T2WI increases the accuracy of pre-operative staging of urinary bladder cancer. |