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العنوان
Role of Magnetic Resonance Imaging in Diagnosis of Pediatric Bone Tumors /
المؤلف
Abd El Khalek, Shrief Ramadan.
هيئة الاعداد
باحث / شريف رمضان عبد الخالق
مشرف / زينب عبد العزيز علي
مشرف / رحاب محمد حبيب
الموضوع
Radiodiagnosis. Magnetic resonance imaging. Bone diseases in children.
تاريخ النشر
2020.
عدد الصفحات
80 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الأشعة والطب النووي والتصوير
تاريخ الإجازة
26/2/2020
مكان الإجازة
جامعة المنوفية - كلية الطب - الأشعة التشخيصية
الفهرس
Only 14 pages are availabe for public view

from 85

from 85

Abstract

Pediatric bone tumors and tumor-like lesions are frequently encountered by radiologists.
The prevalence of primary malignant bone tumors is markedly lower than the prevalence of benign bone tumors in children.
Early diagnosis and treatment are important for improving the quality of life and survival rate of children with malignant bone tumors. If the tumor is diagnosed and treated early, limb salvage can be achieved during the tumor is resected.
The primary assessment of pediatric bone lesions is performed using radiographic imaging and is categorized according to criteria of aggressiveness.
Although radiographs are the primary screening technique, magnetic resonance imaging (MRI) can help narrow the differential or make a specific diagnosis when a lesion is indeterminate or shows signs of aggressiveness. MRI can extend the diagnostic evaluation by demonstrating several tissue components.
Contrast-enhanced MRI can reveal the most vascularised parts of the tumour and MRI guidance makes it possible to avoid biopsing necrotic areas.
It can be used in assessing response to neoadjuvant therapy and further restaging. The post-therapeutic follow-up should also be done using MRI.
This study was conducted on 50 patients with age ranged from 4 to 16 years. 62% of the studied group was males and 38 % was females.
All patients (within the pediatric age) underwent Detailed history analysis ,review of previous radiological investigations as X-RAY, CT or U/S were reviewed and MRI examination of suspected site.
Most of the lesions are seen involving the long bones 64% and 32% affecting the axial skeleton.
Most of the lesions are benign in nature 90% and only 10% are malignant.
Biopsy, histopathological and operative results confirm the radiological diagnosis in suspicious cases.
In Conclusion: At the end of this work, it can be concluded that plain X-ray serves as the principle-screening test for assessment of any pediatric bony lesions. While MRI provide greater specificity in the diagnosis through signal patterns captured in its wide array of modalities and by enhanced pattern. We therefore recommend MRI in the diagnostic work-up of patients with any suspected bone tumors because early and exact diagnosis of all bone pathologies along with sufficient therapeutic consequences may reduce complications and improve outcome of patients especially those with malignant lesions.