الفهرس 
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Abstract
This is prospective observational clinical study that was carried out on patients arrived to Emergency department in Emergency Hospital Mansoura University. Our planned time was one year from January 2019 to January 2020 Aim of the Work: The purpose of study is to determine the Incidence, precipitating factors, and short-term outcome (regarding place of admission, hospital length of stay and mortality rate) of acute Kidney Injury (AKI) in patients presenting with sepsis. Summary :A total of 100 patients presented with sepsis to Mansoura University Emergency Hospital (MUEH) were enrolled in this study. The incidence of sepsis associated AKI (SA-AKI) was 35%. Most of the studied patients were males (60% in AKI group and 63.1% in non-AKI group) who were significantly older in AKI group. Comorbid diseases were more common in AKI group than non-AKI group (88.6% vs. 81.6%): hypertension, COPD, CHF, stroke, and LCF with significant statistical differences in stroke, CHF and LCF distribution in between the 2 groups. The sources of sepsis were closely related to each other in both groups except chest infection which was more prevalent in AKI group with significant statistical difference between the 2 groups. The general examinations items were worse in patients with AKI than non-AKI patients. The qSOFA score revealed that the sepsis was much more severe in AKI patients than non-AKI patients (2.03 ± 0.98 vs. 1.27 ± 0.96) respectively with high significant statistical differences in between the 2 groups. AKI patients were classified using the RIFLE criteria into 28.6% at risk, 45.7% at injury stage and 25.7% at failure stage. The haematological parameters (RBCs,hemoglobin, hematocrit, WBCs, Platelets, Lactate and Serum K+) and ABG parameters (PH, HCO3, PaCO2 and PaO2/FiO2 ratio) were worse in AKI patients than non-AKI patients. There were significant differences only in WBCs, lactate, serum K+ distribution, PH and HCO3 between the 2 groups. Renal functions (GFR, serum creatinine, urea and UOP) snd liver functions (total bilirubin and serum albumin) were worse in AKI than non-AKI patients with high significant statistical differences in renal functions and total bilirubin distribution between the 2 groups. The outcome of the studied cases (place of hospital admission: ward or ICU, LOS and mortality rate) was worse in patients with AKI than non-AKI patients with high significant statistical differences between the 2 groups.