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Abstract Fibroids and adenomyosis represent a common gynecologic problem and result in symptoms that affect quality of life and may result in anemia or other adverse effects. There are many options for treatment, including hormonal therapy, hysteroscopic or abdominal myomectomy, and hysterectomy.In recent years, innovations in gynecology, particularly in the area of medical and minimally invasive therapy, have resulted in new therapeutic options for women with benign uterine lesions. Uterine artery embolization (UAE) is one of these medical advances that has the potential to eliminate the need for surgical intervention. Objectives: The aim of our study was to evaluate the safety and the efficacy of Uterine artery embolization (UAE) as a minimally invasive therapy for management of symptomatic benign uterine lesions (fibroids, adenomyosis) in our community.Patients and methods:This study was a prospective interventional non-controlled study which had been conducted at departments of Obstetrics &Gynecology and Radiology in Mansoura University Hospitals on 40 patients with benign uterine lesions (20 with fibroids including those with fibroid polyps & 20 with diffuse adenomyosis) to assess outcomes after UAE. With the patient under conscious sedation and local anaesthesia, a catheter is inserted into the femoral artery (bilateral catheters are sometimes used). Fluoroscopic guidance is used to manipulate the catheter into the uterine artery. Small embolisation particles are injected through the catheter into the arteries supplying the fibroids, with the aim of causing thrombosis and consequent fibroid infarction. Results: The current study revealed significant clinical improvement by 85% in fibroid patients and by 70% in those with adenomyosis with significant reduction in uterine volume in both group by 20-40%. Moreover, it disclosed an improvement in quality of life satisfaction by about 80%.Fortunately, there were no immediate complications related to the procedure. Most of our patient suffered from short term complication in the form of post embolization syndrome (92%) which was transient and rapidly controlled. There were little serious complications on the long run mostly in the form of vaginal discharge (40%) that was simply treated. |