الفهرس 
Diarrhea
Diarrhea burden:Only 14 pages are availabe for public view
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Abstract
Summary and Conclusions
Summary
Diarrhea means, an increased frequency and/or fluidity of stool relative to the patient’s own habits. Episodes of diarrhea lasting for less than 14 days are defined as acute, while episodes lasting for 14 or more days are defined as persistent.
Acute diarrhea is a major cause of morbidity and mortality in children in developing countries. In most cases, acute diarrhea is caused by acute intestinal infection by viruses, bacteria or parasites.
According to WHO, an estimated 2.5 billion cases of diarrhea occur in children under 5 year old. More than half the cases of diarrhea that occur in Africa and Southeast Asia have poor outcomes or cause death. Despite being an easily preventable and treatable disease, diarrhea is the second leading cause of infant mortality worldwide. Diarrhea alone is greater than that of AIDS, malaria and measles combined.
Early identification of the cause of diarrhea is important, particularly in diarrhea related to inflammatory processes, in order to determine the appropriate therapy. Doctors often have difficulty in differentiating between bacterial and non-bacterial diarrhea. As such, a new, simple, fast, and accurate biomarker is needed to diagnose infectious diarrhea. Currently, there is no such biomarker to detect bowel inflammatory processes. Fecal biomarkers may be interesting tools, as stool flows along the intestinal mucosa