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العنوان
Evaluation of epicardial adipose tissue and left ventricular function in relation to body composition, insulin resistance and serum chemerin in obese children /
المؤلف
El-Moslemany, Farhat El-Sayed.
هيئة الاعداد
باحث / فرحات السيد المسلمانى
مشرف / هاله محمد فوزى المرصفاوى
مشرف / أحمد عبدالخالق محمد
مشرف / نانيس عبدالبديع سالم
الموضوع
Obese Children. Insulin Resistance. Serum Chemerin. Left Ventricular Function. Obesity in children. Bulimia Nervosa - therapy. Bulimia - therapy.
تاريخ النشر
2020.
عدد الصفحات
online resource (207 pages) :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
1/1/2020
مكان الإجازة
جامعة المنصورة - كلية الطب - قسم طب الاطفال
الفهرس
Only 14 pages are availabe for public view

from 207

from 207

Abstract

Obesity is an emerging health problem of growing importance. In 2012, more than one third of children and adolescents were overweight or obese and in the past 30 years, childhood obesity has more than doubled in children and quadrupled in adolescents.. In a population-based study, 70% of obese youth (5-17 year) had at least one CVD risk factor, and 39% had two or more .Additional comorbidities of obesity include endocrinal abnormalities associated with increased risk of impaired glucose tolerance, insulin resistance and type 2 diabetes. Epicardial fat (EF) is considered a passive lipid-storage unit, and also it is actively involved in the lipid and energy homeostasis of the myocardium. Magnetic resonance imaging (MRI) is considered the gold standard for the assessment of total body fat and reference modality for the analysis of ventricular volumes and mass The aim of the work: to evaluate Epicardiac adipose tissue in obese children using CMR. Study the relationship of Epicardiac adipose tissue and anthropometric measurements, body composition, insulin resistance indices , serum level of chemerin and left ventricular function as assessed by speckle tracking echocardiography in obese childrenType of study: cross sectional study Materials and Methods: 20 obese pre-pubertal children (simple obesity) their ages ranged from (5-12 years) were enrolled consecutively from pediatric Endocrinology outpatient clinic, Mansoura University Children`s Hospital (MUCH) and 20 apparently healthy children of matched age and sex serve as control group from March 2017 to March 2019.