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Abstract Coronary stents stared with BMS but it had associated with intrastent restenosis rates of 20-30% which requiring re-intervention ,so DES developed to overcome restenosis and TVR firstly by the first-generation DES with SES and PES but increased rates of stent thrombosis were reported with first-generation DESs, so 2nd generation DESs (EES,ZES,BES….etc) with thinner struts, different anti-proliferative drugs and polymers were subsequently developed to reduce the rate of long-term cardiac adverse events. More recently a fully BRS developed and its use is increasing rapidly. However, further randomized controlled trials are still needed to compare the long-term clinical benefits with new DESs. In our study we evaluated the impact of length and diameter of drug eluting stents on clinical outcome in patients with LAD single stent .at 6 months of implantation in 100 patients who had PCI for different indication. We found that most of the primary PCI patients had proximal LAD lesion with thrombus and reduced Ejection fraction but most of the patients with urgent or elective PCI had more mid LAD lesions and preserved Ejection fraction. One of the more significant findings to emerge from this study is that long stents more than 30mm might be associated with MACEs more than short stents less than 30mm. It was also shown that stent diameter had no effect on the outcomes. So according to our study we concluded that long second generation DESs in LAD coronary artery have worse outcomes. which may be due to multifactorial effect including patient presentation and stent length. |