الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Liver resection has been considered as one of the most challenging and bloody operation in Surgery for a long time. However, with refinement of surgical techniques, development of new energy-sealing devices, careful patient selection and optimal post-operative care, a significant improvement in the outcome of liver resection has been achieved. Nowadays, the mortality rate post-hepatectomy dropped to less than 5%. Furthermore, the introduction of minimal access surgery (Laparoscopic and robotic approaches) in different types of hepatectomies has dramatically decreased the post-operative morbidity.
The aim of this study was to assess the safety and feasibility of laparoscopic liver resection for liver tumors, to compare this approach with the open liver resection technique regarding operative time, blood loss, postoperative complications and hospital stay, in addition to evaluate the short-term oncological outcome of laparoscopic liver resection for hepatocellular carcinoma.
This study was carried out on forty patients with liver tumors in the Hepatobiliary-pancreatic surgery and transplantation department, Kyoto University Hospital, Japan and Hepatobiliary-pancreatic Surgery unit, Alexandria University Hospital, Egypt. All patients were followed up for 12 months. They were divided into two groups: group A; managed by Laparoscopic liver resection (LLR) and group B; managed by open liver resection (OLR).
There was no significant difference between both groups regarding the demographic characteristics, indications of liver resection, tumor site and number and type of liver resection (anatomical or non-anatomical). However, the preoperative tumor markers were significantly higher in group B and also tumor size was significantly larger in group B.
The operative time was shorter in the laparoscopic group but not statistically significant, whereas, the intraoperative blood loss was significantly more in group B. To exclude all confounding factors of significant blood loss, multivariate analysis was performed and showed that open approach for liver resection was an independent risk factor for significant blood loss intraoperatively.