الفهرس 
Hypertrophic scarsOnly 14 pages are availabe for public view
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Abstract
A cutaneous scar is defined as dermal fibrous replacement tissue that results from a wound that has healed by resolution rather than regeneration .The ultimate goal of the wound-healing process is the regeneration of the injured skin without scar formation, with new tissue having the same structural, aesthetic, and functional attributes as the original uninjured skin. Scars are often considered trivial, but they can be disfiguring and aesthetically unpleasant and may cause itching, tenderness, pain, and physical deformity as a result of skin scar contractures can be disabling. Other psychosocial sequels include development of post-traumatic stress reactions, loss of self-esteem and stigmatization, leading to diminished quality of life. Hypertrophic scars are typically raised, red or pink. They become brownish-red and then pale as they age, sometimes pruritic, but do not exceed the margins of the original wound and usually subside with time . Galectin-7 is a prototype galectin that appears in the epidermis, coinciding with epidermal stratification as a marker of keratinocyte differentiation. Galectin-7 is thought to play a role during wound healing, functioning as a regulator of keratinocyte proliferation and migration that is central in maintaining and restoring epidermal homeostasis.The aim of the work was to evaluate serum level and tissue expression of galectin-7 in patients with hypertrophic scars compared with control subjects.This was a case control study which included 30 patients, suffering from hypertrophic scars (group A). In addition, 30 apparently healthy individuals of matched age and sex were chosen as a control group (group B). Patients were selected from the outpatient clinic of Dermatology, Venereology and Andrology department of Banha University Hospitals in the period from January 2019 to April 2019, Serum and tissue level of Galectin-7 were measured using Human Galectin-7 ELISA Kit supplied by Biokit Company, China.