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العنوان
ROLE OF PET/CT IN DETECTION OF TUMOR OF UNKNOWN ORIGIN/
الناشر
Ain-Shams University.
المؤلف
Elsayed,Khadija Reda Saber .
هيئة الاعداد
باحث / خديجة رضا صابر السيد
مشرف / خالد عصمت علام
مشرف / عمر فاروق كامل
مشرف / أحمد حسن سليمان
مشرف / هدى فتحي السيد
تاريخ النشر
2020
عدد الصفحات
69.p;
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الأشعة والطب النووي والتصوير
تاريخ الإجازة
1/4/2020
مكان الإجازة
جامعة عين شمس - كلية الطب - Radio diagnosis
الفهرس
Only 14 pages are availabe for public view

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Abstract

Purpose: To evaluate the role of combined positron emission tomography and computed tomography (PET/CT) imaging in the detection of tumors of unknown origin.
Methods: This study included 20 cases presented with pathologically proved metastases of unknown primary or with clinic-radiological suspicion of metastases with unknown primary.
Results: The number of patients with true positive primary tumor sites was 14 (70%), 2 patients with false-positive results (10%), 2 patients with true negative results (10%) and 2 patients with false-negative results (10%). A sensitivity of 87.5% was achieved, with a specificity of 50% and a total accuracy of 80%. The Positive predictive value was 87.5%%, while the negative predictive value was 50%. The detection rate of the origin of the primary tumor was 70%.
Conclusion: whole-body FDG-PET/CT has to be considered a useful tool in evaluating metastases from UPT, allowing identification of primary tumors and modifying the stage of the disease and affect the management.