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العنوان
Assessment of the role of total antioxidant capacity and troponin I as possible predictors for phosphides -induced cardiotoxicity/
الناشر
Faculty of medicine.
المؤلف
Abdel Wahab,Marwa Mohamed
هيئة الاعداد
باحث / مروه محمد عبد الوهاب
مشرف / أ.د. سوسن عبد الفتاح شلبى
مشرف / أ.د. اجلال حسن العوضى
مشرف / د. رانيا حسين محمد
تاريخ النشر
2020
عدد الصفحات
218 P.:.
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
علم الأمراض والطب الشرعي
تاريخ الإجازة
1/1/2020
مكان الإجازة
جامعة عين شمس - كلية الطب - السموم الاكلينيكية
الفهرس
Only 14 pages are availabe for public view

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from 217

Abstract

The mean duration of hospital stay was 2.07 days and there was non-significant difference between studied groups.
Outcome of the studied patients was determined as the following ; the majority of patients (92 %) recovered and discharged without any complications and only 2.7% died. eleven cases (5.9%) had shock, 8 cases (4.3%) developed cardiac arrest, 8 cases (4.3%) developed respiratory failure, and 11 cases (5.9%) developed myocardial ischemia.
The area under the curve was 0.765(0.697 to 0.824), the best cut off point was ≤0.07 µmol/l, with sensitivity of 100% and specificity of 63.54% for TAC to predict mortality among studied patients.
The area under the curve was 0.97(0.94 to 0.99), the best cut off point was ≥2.95ng/ml, with sensitivity of 100% and specificity of 90.06% for troponin I to predict mortality among studied patients.
The current study concluded that Initial TAC ≤0.07µmol/l and troponin I ≥2.95ng/ml levels could be useful in predicting development of oxidative damage, cardiotoxicity and mortality after metal phosphides poisoning.
The present study recommended the use of TAC and troponin I levels in patients with acute metal phosphides toxicity for prediction of cardiotoxicity and mortality.