الفهرس 
AcknowledgementOnly 14 pages are availabe for public view
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Abstract
BA is one of the most serious diseases of the CNS.BA is still associated with high morbidity, including seizures (up to 80%), persistent altered mental status, and focal motor deficits. BA still continues to be a significant problem in the developing world due to large scale poverty, illiteracy, and lack of hygiene. Currently, in high-income countries the original forms of intracranial suppurative disease (i.e., BA, empyema, and purulent ventriculitis) are so uncommon that most young neurosurgeons are unfamiliar with this form of pathology and recognizing the need at times for judicious, complex, and aggressive surgical management. The infectious origin of the BA causes significant damage to the CNS, because of its incapability of mounting a sufficient defense against the pyogens, leading to pyogenic abscess. However, the trends of decreasing incidents are reported due to the improvement in world sanitation at present. As has been stated previously, although there have been breakthrough advances in neuroimaging, neurosurgical techniques, neuroanesthesia, microbiological isolation techniques, and antibiotic therapy, bacterial BAs can be fatal. This clinical prospective descriptive study was done during two years period which aimed to study clinical presentation, complication and outcome of management brain abscess. All patients treated with stereotactic aspiration using a stereotactic device (CRW) R and CT scanning using (GE Bright Speed) R unit. This study included 20 patients had brain abscess, 14 patients (70%) were males and 6 patients (30%) were females. Patients included in the study had different ages with the youngest was 5 years old and the oldest had 55 years old with Mean ± SD (7.7± 3.2). As regard site of brain abscess showed that, the commonest sites for brain abscess were brain stem (25%) and basal ganglia (25%).Results of the present study showed that, solitary brain abscess was more frequent than multiple abscesses. Solitary brain abscess was presented in 85%Vs 15% of multiple abscesses. Data of our study showed that, out of 20 patients had brain abscess; the most presenting complain was headache in 80% of cases, while limb weakness found in 50% of cases, vomiting were in 30% of patients and as well as fits in 30% of patients. Despite of all this fever, counted only 10% of our patients. Examination of the studied patients with BA revealed that, unequal pupil was found in a half of our studied groups, while weakness was found in 40% of cases and papilledema was in only 20%. Disturbed conscious level in 70% of cases. According to the predisposing conditions of BA,Our study recorded that 6 patients (30%) of our patients had cardiac problem associated with brain abscess, while chest infection presented in 4 cases (20%) and otogenic cause was found in 3 cases(15%). There were 4 cases (20%) with unknown causes for brain abscess formation. Post traumatic cases found in 10% while only 5% had post-surgery leading causes. Our recorded data of patients for GCS showed that, 65% of them had GCS score from 12 to 15. While 25% of them had GCS ranged from 8 to 12 and 10% of cases had GCS less than 8. The only complication that occurred post-operative was haemorrage in only two patients (10%).Early postoperative follow up CT of our cases within (1-3) days showed that size of brain abscess was decreased in 50% of cases, but only 10% was still the same, while 40% resolved completely. Culture and sensitivity results, were positive in 45% of patients and negative in 55% of them. As regard follow-up CT of operated brain abscess patients after 6 months we noted that, 90% of our cases had complete recovery, while 10% had recurren from the result and data of our present study we can conclude that Stereotactic aspiration of brain abscess is a safe and effective method for treatment of brain abscess. It is more effective with a good antibiotic coverage for resolving brain abscess completely. Stereotactic aspiration is the modality of choice in Abscesses in deep and/or eloquent structures. Immunocompromised patients with brain abscess. Multiple brain abscesses.