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Abstract There were 351 cases included, 290 cases Anterior circulation stroke (ACS) and 61 cases posterior circulation stoke (PCS), with 65 cases DROP out during the 3 months follow up period. Of these 351 cases, males were more prevalent (62.5%) the mean age of the cases was 62.7 (SD ± 11.3) and among the assessed risk factors. hypertension was most prevalent (64.1%), with all risk factors being identified as independent factors. The initial NIHSS was statistically lower in PCS group compared to ACS group (7.7, 10.5, p-value <0.001), with significant improvement across the time points (hrs, 24 hrs & 7 days) within each group (p-value <0.001) but not between the two groups. The mean OTD and DTN was statistically non-significant between the ACS and PCS, (mean OTD 2.1,2.1 and p-value 0.992, mean DTN 50.6, 45.6 and p-value 0.105 respectively). As regards the etiology, large vessel disease was most common upon ACS (47.2%) and small vessel disease most prevalent among PCS (36.10%, p-value 0.03), with small vessel disease being of better functional outcome compared to large vessel disease in ACS (p-value <0.001) and cardioembolic showing significant better functional outcome in PCS compared to ACS (p-value < 0.05) and vice versa as regards the large vessel disease (p-value < 0.05) The PCS cases had statistically good functional outcome (MRS ≤ 2) more than ACS (93.8%, 70.2% respectively, p-value 0.001) In conclusion, our study showed that the prevalence of PCS is around 20 % and that the outcome as regards either the NIHSS at discharge and MRS score of PCS patients receiving IVT is better than the ACS patients. |