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العنوان
Prevalence and Outcome of Alteplase in Posterior Cerebrovascular Stroke Versus Anterior Cerebrovascular Stroke/
الناشر
Ain Shams University.
المؤلف
Attiah,Nourhan Abdelmohsen Taha .
هيئة الاعداد
باحث / نورهان عبد المحسن طه
مشرف / هالة محمود الخواص
مشرف / محمد أمير ترك
مشرف / تامر محمود رشدي
تاريخ النشر
2020
عدد الصفحات
138.p;
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب النفسي والصحة العقلية
تاريخ الإجازة
1/4/2020
مكان الإجازة
جامعة عين شمس - كلية الطب - Neuropsychiatry
الفهرس
Only 14 pages are availabe for public view

from 139

from 139

Abstract

There were 351 cases included, 290 cases Anterior circulation stroke (ACS) and 61 cases posterior circulation stoke (PCS), with 65 cases DROP out during the 3 months follow up period.
Of these 351 cases, males were more prevalent (62.5%) the mean age of the cases was 62.7 (SD ± 11.3) and among the assessed risk factors. hypertension was most prevalent (64.1%), with all risk factors being identified as independent factors.
The initial NIHSS was statistically lower in PCS group compared to ACS group (7.7, 10.5, p-value <0.001), with significant improvement across the time points (hrs, 24 hrs & 7 days) within each group (p-value <0.001) but not between the two groups.
The mean OTD and DTN was statistically non-significant between the ACS and PCS, (mean OTD 2.1,2.1 and p-value 0.992, mean DTN 50.6, 45.6 and p-value 0.105 respectively).
As regards the etiology, large vessel disease was most common upon ACS (47.2%) and small vessel disease most prevalent among PCS (36.10%, p-value 0.03), with small vessel disease being of better functional outcome compared to large vessel disease in ACS (p-value <0.001) and cardioembolic showing significant better functional outcome in PCS compared to ACS (p-value < 0.05) and vice versa as regards the large vessel disease (p-value < 0.05)
The PCS cases had statistically good functional outcome (MRS ≤ 2) more than ACS (93.8%, 70.2% respectively, p-value 0.001)
In conclusion, our study showed that the prevalence of PCS is around 20 % and that the outcome as regards either the NIHSS at discharge and MRS score of PCS patients receiving IVT is better than the ACS patients.