الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 117 |  |  |
| | | from | 117 | | |
Abstract
Purpose: This study is done to study morphological structure of ill defined choroidal neovascularization with Fluorescein angiography by Optical coherence tomography angiography. Patients & Methods: This prospective cross sectional, non randomized, non interventional study that was done on 48 eyes of 35 patients who diagnosed to have CNV by fundus fluorescein angiography, optical coherence tomography and optical coherence tomography angiography imaging was performed using “Topcon Corp, Japan”, On OCTA imaging, 6×6 mm scanning areas centered on the fovea were used. Segmentation of the retina and choroid within the macular area. After full history and complete ophthalmologic examination, FA, OCT and OCTA was done for all patients after pupillary dilatation with Mydrapid eye drops (tropicamide 1%). Results: Our results showed 35 patients, 18 of them are males and 17 of them are females. In this study, OCTA was superior to FFA in detection clear vascular network, the exact location and classification of CNV. It showed statistical significance difference (p value = 0.001). As occult CNV and CNV suspicious in FFA appeared mainly as sharply defined, dense interlacing neovascular membrane (type I) that had more volumetric angiographic information of CNV in choriocapillaries. And only one eye appeared as a small, high flow vascular tuft of small caliber vessels that originating from deep capillary plexus of the outer retina. The feeder vessel can be appreciated, communicating with the inner retina (type III) that had more volumetric angiographic information of CNV in outer retina. Comparison between OCT & OCTA in RPE overlying CNV area showed statistical significance difference (p value = 0.001). AS type I CNV in OCTA has intact RPE in OCT and type II & III in OCTA had disrupted RPE in OCT. In this study, The most common cause for type I CNV was wet AMD and the most common cause for type II CNV was high myope. It showed statistical significance difference (p value = 0.007). In this study, the best corrected visual acuity in different types of CNV showed statistical significance difference (p value = 0.019). As type II (classic myopic CNV) had poorer vision than type I (occult CNV in wet AMD).