الفهرس | Only 14 pages are availabe for public view |
Abstract Electrophysiologic screening for neuropathy in neurologically asymptomatic chronic hepatitis C virus patients ; peripheral neuropathy and optic neuropathy Background : Hepatitis C virus and its consequent chronic outcomes are the foremost endemic health problems affecting Egypt today. Nerve conduction studies (NCSs) serves as the gold standard test in detection of subclinical neuropathy Objectives : This study was undertaken to assess the prevalence and characteristics of peripheral and optic neuropathy in in neurologically and ophthalmologically asymptomatic chronic HCV patients. Patients and methods ; Patients group included 40 patients with HCV infection; 16 females and 24 males. and included 20 volunteers of both sexes (12 females and 8males). They were in perfect general health. Results: The results reveled a total of 28(70%) of our patients were diagnosed to have PN by electrophysiological examination, and late response showed that peripheral neuropathy was significantly present in 20 (50%) of the studied patients. Conclusion: Our study reported that sensory conduction abnormalities in the sural nerves were more frequent than that of the upper limbs. And Sensory conduction studies abnormalities in the upper limbs were more detected than motor conduction abnormalities. Also, motor conduction studies of the common peroneal nerves were more affected than that of the upper limbs. and the predominant pattern of neuropathy was axonal type, especially in lower limbs. In the upper limbs, both demyelinating and axonal types were detected. As for the clinical predominant type, it was sensory pattern of neuropathy. |