الفهرس 
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Abstract
Seronegative spondyloarthropathy is a group of chronic inflammatory rheumatic diseases that predominantly affect the axial skeleton. This group comprises disease entities like ankylosing spondylitis, reactive arthritis, psoriatic arthritis, arthritis associated with chronic inflammatory bowel disease (Crohn’s disease and ulcerative colitis), and undifferentiated spondyloarthropathies. With the advent of imaging modalities increased awareness of this entity, and presence of new treatment options, more and more cases of spondyloarthropathy are being diagnosed at an early stage, as imaging plays an important role in the diagnosis. Involvement of sacroiliac (SI) joint is considered a hallmark for diagnosis of seronegative spondyloarthropathy and is usually the first manifestation of this condition. Thus, detection of sacroiliitis helps in early diagnosis and treatment.
The treatment of SIJ pain remains a therapeutic challenge.Besides physiotherapy and systemic therapies including nonsteroidal anti-inflammatory drugs (NSAIDs), Disease Modifying Anti –Rheumatic Drugs (DMARDs) and biological agents, intra-articular and periarticular injections of SIJ, radiofrequency neurotomy, and surgical fusion are often performed for pain relief.
SIJ steroid injection is a commonly used technique and has been found to be effective to treat SIJ pain. But due to its short-term effect, there is clearly a need to investigate treatments that have a longer-lasting effect and also directly address the disease process itself. Current research efforts aim at modifying the rate of joint healing using biological healing factors, which are various growth factors found abundantly in the human blood, especially in platelets.
This study aimed to evaluate the efficacy of ultrasound-guided (USG) sacroiliac injection of PRP for sacroilitis in seronegative spondyloarthropathies versus triamcinolone acetonide injection and follow up of the patients clinically and radiologically after injection.
Seventy patients with a sero-negative axial spondylo-arthropathy diagnosed according to the International Classification Criteria for axial spondylo-arthropathy who had attended the outpatient clinic of physical medicine, rheumatology & rehabilitation department, Menoufia university hospitals from 2017 to 2019, were included in this study.
Patients were randomly divided into 2 groups:
group I received 1ml of triamcinolone acetonide (40mg) and 1 ml of 2% lidocaine intra-articular sacroiliac joint guided US injection.
group II received 2-3 ml of PRP intra-articular sacroillic joint guided US injection.
The patients were evaluated before the procedure, 4 & 8 weeks after injection for pain intensity by VAS & MODQ scores & MRI STIR technique oblique coronal view 8 weeks after.