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Abstract Aluminium phosphide (ALP) is a cheap, effective and commonly used pesticide for protection of stored grains. However, it is now one of the most common causes of poisoning among agricultural pesticides human poisoning with ALP is associated with very high mortality rate. Death rates are highly variable, ranging from 30% -100% even in well prepared hospitals. The increased incidence of acute ALP poisoning and its high mortality are real challenges for health professional staff in developing countries. There is no specific antidote and treatment is mainly supportive. Hence, evaluation of new treatment modalities is necessary, in order to decrease the rate of mortality and morbidity. The aim of this study was to evaluate the efficacy and safety of saline versus some vegetable oils in gastric decontamination in acute almuniuim phosphide poisoning This study was a randomized controlled trial conducted on 60 patients presented with acute aluminium phosphide (ALP) poisoning. The participants were recruited from Tanta Poison Control Unit -Emergency Hospital -Tanta University, starting from the beginning of April 2018 to the end of January 2019. Sixty patients were randomly allocated into three equal groups (I, II and III) with 20 patients in each group by using the sequentially numbered, opaque sealed envelopes method. In group (I) patients were treated by saline and sodium bicarbonate in gastric lavage as a control group. In group (II) patients were treated by sweet almond oil and sodium bicarbonate in gastric lavage. In group (III) patients were treated by coconut oil and sodium bicarbonate in gastric lavage in addition to the usual conventional treatment in the three groups. |