الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
The danger of electricity returns to its wide spread and great use in our daily life. Moreover, electric current is invisible and could induce injuries at any part of the body or lead directly to death mostly without leaving any detectable marks. The degree of damage caused by electricity depends on type and intensity of electric current and the nature of exposed cells or tissues. The electrical shock could affect skin, central nervous system, cardiovascular system, skeletal muscles and many other internal organs.
Apoptosis, a gene-regulated form of cell death, is critical for normal development and tissue homeostasis. A major component of the apoptotic machinery involves a family of aspartic acid-directed cysteine proteases, called caspases (cysteinyl aspartate specific proteinases). These enzymes cleave multiple protein substrates, leading to the loss of cellular structure and function and ultimately resulting in cell death. The caspase family comprises at least 14 enzymes in mammalian cells. In particular those components including caspase-3 and -8 have a relevant role in apoptosis.
This study included 120 male & female albino rats with average weight 200-250 gm were used. This study was done to detect histopathological changes in testes and ovaries and to evaluate the expression of FABP1 (fatty acid binding protein 1) and Caspase 3 in these organs of electrically injured rats by non-fatal electrical. The rats in this study were divided into six groups (each containing 20 rats 10 males & 10 females). group 1 is the control group in which normal rats not exposed to electric current and were sacrificed at the same period of their corresponding experimental groups. And non-fatal electrocution groups (Gp 2, Gp 3, Gp 4, Gp5 and Gp6) exposed to alternating electric current which was not of lethal intensity (220v for 60 seconds) then sacrificed immediately, after 4h, 24h, 72h and 7 days respectively.
The results of histopathological changes detected in the testes of the rats were in the form of decreased number of seminiferous tubules, degeneration in cells of seminiferous tubules, disruption of the basement membrane of the tubules, loss of interstitial cells of Lydig, congestion in stromal blood vessels and hemorrhage. While those detected in the ovaries of the rats were in the form of decreased number and size of ovarian follicles, hyaline degeneration, congestion in stromal blood vessels and hemorrhage and there were statistically significant results as regard those changes.
The immunohistochemical expression of caspase 3 in testicular tissues show significant increase in percentage of its expression among six groups and also there are significant increase in caspase 3 expression among six groups as regarding the immunohistochemical expression of caspase 3 in ovarian tissues.
The immunohistochemical expression of FABP1 in testicular tissues show significant decrease in percentage of its expression among six groups and also there are significant decrease in FABP1 expression among six groups as regarding the immunohistochemical expression of FABP1 in ovarian tissues.