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العنوان
Effects Of Eugenol And Beta_Resorcylic Acid On Invasion And Virulence Genes, Expression Of Multi-Drug Resistant Avian Campylobacter Jejuni Isolates /
المؤلف
El-Malt, Rania Mohamed Saied Ali.
هيئة الاعداد
باحث / رانيا محمد سعيد على الملط
مشرف / أحمد محمد عمار
مشرف / السيد يوسف محمد النعناعي
مشرف / مروة ابراهيم ابراهيم
مشرف / عطية عبدالله الجداوي
الموضوع
Eugenol. Bacteriology.
تاريخ النشر
2020.
عدد الصفحات
204 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
البيطري
تاريخ الإجازة
1/1/2020
مكان الإجازة
جامعة الزقازيق - كلية الطب البيطرى - بكتــريولوجيـــــا
الفهرس
Only 14 pages are availabe for public view

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Abstract

Chickens are recognized as the primary reservoir of thermotolerant Campylobacter spp. and they are responsible for an expected 80% of human campylobacter infections. Therefore, intervention procedures for controlling virulent and resistant Campylobacter spp. in chickens have been created to diminish the product contamination and subsequently the rate of campylobacter diseases in humans. With expanding the consumer requests for safe and natural products with negligible preservatives, important researches are being conducted to investigate the capability of natural antimicrobials such as phytochemicals for controlling C. jejuni in chickens.
Therefore, the aim of the present study was to assess the efficacy of beta-resorcylic acid and eugenol (at SIC values) on C. jejuni invasion of chicken intestinal epithelial cells and to investigate their effects on the expression of critical virulence genes of multi-virulent and MDR C. jejuni isolates from chicken origin via qRT-PCR assay. The tested isolates were genetically correlated with the human ones.
In the present work, a total of 113 campylobacter isolates (32.8%) were recovered from 345 different samples collected from human (children stool swabs) and chicken (cloacal swabs, cecal parts, neck skin, liver, gizzard and thigh and breast meat).