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العنوان
Synthesis And Biological Evaluation Of Some New Heterocyclic Systems /
المؤلف
El-Saadaney, Ahmed Mohamed.
هيئة الاعداد
باحث / Ahmed Mohamed El-Saadaney
مشرف / Ahmed Ali Fadda
مشرف / Elsherbiny Hamdy El-Sayed
مناقش / Ehab Abdel-Latif
مناقش / Hatem El-Sayed Gafaar
تاريخ النشر
2020.
عدد الصفحات
148 p. ;
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Multidisciplinary تعددية التخصصات
تاريخ الإجازة
7/3/2020
مكان الإجازة
جامعة بورسعيد - كلية العلوم ببورسعيد - Chemistry Department
الفهرس
Only 14 pages are availabe for public view

from 148

from 148

Abstract

The aim of the present work is to synthesize some new pyrazolopyrimidine and sufathiazole derivatives to form new pharmacophore for antimicrobial agents. This work divided into two parts:
Part 1
Synthesis and Antimicrobial Evaluation of Some New Pyrazolo[1,5-a]pyrimidine, Pyrazolo[1,5-a]quinazoline and Pyrazolo[1,5-c]triazine Derivatives Containing Sulfathiazole Moiety
We have been interested to study the intermediate N-(4-(N-(thiazol-2-yl)sulfamoyl)phenyl)- carbonohydrazonoyl dicyanide (2) as starting material for the synthesis of new heterocyclic compounds, which prepared by diazotization of sulfathiazole1 and coupling of the diazonium salt with malononitrile.