الفهرس 
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Abstract
Gastrointestinal diseases and particularly the diarrheic syndrome as a result of either colibacillosis or salmonellosis are the principal problems causing mortality in industrial fattening rabbit farms.
The current study was planned to assess the application of nanotechnology in the veterinary field and as a result of the emergence of multiple antibiotic resistance due to over and misuse of antibiotics, our study planned to evaluate the antibacterial activity of natural-based nanoparticles (chitosan-propolis-nanocomposite) against S. typhimurium and E. coli infections and their adverse effects as oxidative stress and hepato-nephrotoxicity in rabbits.
In vitro studies:
The smallest size, spherical in shape and stable nano particles were obtained through the characterization of chitosan nanoparticle and nanocomposite by FTIR fingerprint spectros¬copy, zeta potential and TEM microscopies. Also, safety of these particles was achieved through the culture on Vero cell line. Nanomedicine against three pathogens in veterinary medicine could be approved in vitro by MIC demonstrating the.