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العنوان
Prognostic Value of Ambulatory Blood Pressure Monitoring Pattern in Post-Partum Pre-Eclamptic Patients /
المؤلف
Fahmy, Mariam Rashed.
هيئة الاعداد
باحث / مريم راشد فهمى يسين
مشرف / عمرو على احمد يوسف
مناقش / حسام حسين العربى
مناقش / احمد بغدادى
الموضوع
Post-Partum Pre-Eclamptic Patients.
تاريخ النشر
2020.
عدد الصفحات
80 p. ;
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض القلب والطب القلب والأوعية الدموية
الناشر
تاريخ الإجازة
28/10/2020
مكان الإجازة
جامعة أسيوط - كلية الطب - Cardiology
الفهرس
Only 14 pages are availabe for public view

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Abstract

Preeclampsia is a pregnancy-specific disease that complicates 2% to 8% of all pregnancies; Preeclampsia may be considered a ‘risk marker’ for later-life cardiovascular diseases. (Pechère-Bertschi et al. 2012) Correlation between BP and target organ damage, vascular risk, and long-term patient prognosis is stronger for measurements derived from around-the-clock ABPM than in-clinic daytime ones. A sleep BP mean is an independent and much better predictor of cardiovascular disease risk than either the awake or 24 h means. (Hermida et al. 2016) Women with previous PE have a greater risk of hypertension, higher night time BP values, blunted nocturnal BP fall. These factors may contribute to their higher cardiovascular risk after pregnancy. (Polónia et al. 2014) Women with diminished nocturnal BP decline (non-dipper pattern) have a significantly worse prognosis than the ones with a normal dipper pattern. ( Hermida at al. 2007) Nocturnal hypertension in preeclamptic patients is associated with endothelial damage which is a recognized pathogenic factor for atherosclerosis and history of preeclampsia is a risk factor for cardiovascular disease. (Bouchlariotou et al. 2008) In our study, was to explore the association between 24-hour blood pressure monitoring and subclinical cardiovascular affection (by echocardiography) 3 months postpartum in preeclamptic women. Our study focus on the prognostic cardiovascular risk of preeclampsia that persists after preeclampsia predicted by ambulatory blood pressure monitoring and evaluation of cardiac function in post preeclamptic women by 2D echocardiography. IN our study sixty-four women were enrolled in the study, based on 24 hours- ABPM 3 months post-partum; out of the studied women, 45 (70.3%) women were dippers and 19 (29.7%) women were non- dippers. It was noticed that diastolic dysfunction presented in 14 (73.87%) of non-dippers while none of dippers had diastolic dysfunction. It was noticed that moderate and severe preeclampsia had no significant differences as regarding the systolic function but those women with severe preeclampsia had higher frequency of non- dipper (35.5% vs. 24.2%; P= 0.02) and diastolic dysfunction (29% vs. 15%; P= 0.01) in comparison to those women with moderate preeclampsia. ConclusionWe have found a positive relation between preeclampsia and non-dipping profile by ABPM, also a positive association between preeclampsia and cardiac diastolic dysfunction assessed by 2D echocardiography. We concluded that severe preeclampsia and recurrent preeclampsia were significant predictors for non-dipping profile and diastolic dysfunction in such women. So there is an increasing cardiovascular prognostic risk which is higher in recurrent and severe preeclampsia.