الفهرس 
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Abstract
Aim of the study: to compare clinically and radigraphically the topical application of melatonin and grafless crestal sinus lift. Material and methods: twenty patients with missing maxillary posterior teeth to receive 20 implants underwent this crestal sinus lift technique performed using an SCA KIT. group I included 10 implants combined with local application of melatonin gel at the osteotomy site surface while group II included 10 implants without melatonin gel application. The mean residual bone height was 7.1 mm (range: 6 mm to 8.13 mm). Immediately after the implant placement, implant stability test was performed using the Osstell Monitor, Patients were recalled for follow up at 3, 6, and 9 months. Radiographic and clinical examinations were conducted during follow-up Result: All implants were considered successful after 9 months of follow-up. A high statistically significant difference in bone density and implant stability in group I with local melatonin application (P = 0.001). Conclusion: topical application of melatonin increase bone density and inhibit bone resorption around implants in crestal sinus lift techniques.