الفهرس | Only 14 pages are availabe for public view |
Abstract Cardiovascular diseases are currently the leading cause of death in industrialized countries and are expected to become so in developing countries.[1] Left ventricular (LV) dysfunction is the single strongest predictor of mortality and one of the most frequent and deadly complications following ST segment elevation myocardial infarction , and this complication has been greatly reduced in the era of primary PCI.[3] This work aims to study and explore the left ventricle ejection fraction improvement after revascularization with percutaneous coronary intervention (PCI) and the predictive factors for left ventricle ejection fraction improvement and diastolic function. . Recent studies have explored the prognostic role of TDI-derived parameters in major cardiac diseases, such as coronary artery disease (CAD) and heart failure (HF) [102]. This study was conducted on 100 patients with ischemic (HFrEF) who had complete revascularization with percutaneous coronary intervention (PCI), had survived at least 90 days and had undergone echocardiography review. Patients will be divided into 2 groups according to change of LV EF after 3 months: • group 1 (50 patients): Those with improvement of (LV EF).. • group 2 (50 patients): Those without improvement of (LV EF) or deterioration of ( LV EF). Summery and Conclusio n 95 The study was conducted from April 2019 to April 2020. The two groups were assessed as demographic data, laboratory investigations, angiographic results and echocardiographic parameters before and after PCI for 3 months. Echocardiography assessment included: • Ejection fraction by Teichholz method. • Tissue Doppler (E/e’) and S’. This study had found that improvement of LV systolic and diastolic dysfunction has many determents. In this study we had observe some of this determents that affect improvement of LV systolic and diastolic function. Regarding demographic data male sex showed great effect in improvement of LV function. Other predictors for improvement of LV function were Diabetes mellitus, CKD, shorter time between presentation and PCI ,present of angina pain ,normal Ecg findings Angiographic result was very important like absent of CTO and presence of collaterals, single vessel affected. Other parameters that was not significant in prediction of LV function included age, smoking, Hypertension, dyslipidemia. |