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العنوان
Study the interaction of some medical oils with antibiotics and its effect on some pathogenic microorganisms /
المؤلف
Mohamed, Eman Abdalla Abohashem.
هيئة الاعداد
باحث / إيمان عبد الله أبو هاشم محمد
مشرف / محمود محمد هزاع
مناقش / محمد عثمان عبدالمنعم
مناقش / إبراهيم محمد عبدالعزيز
تاريخ النشر
2020.
عدد الصفحات
115p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
علوم النبات
تاريخ الإجازة
1/1/2020
مكان الإجازة
جامعة بنها - كلية العلوم - النبات
الفهرس
Only 14 pages are availabe for public view

from 130

from 130

Abstract

SUMMARY
For many years, the battle between humans continues and the multiplicity of infections and disease-causing diseases. Emerging on the battlefield as one of the most important challenges facing human health is bacterial resistance and its rapid rise. These have become a major global public health concern revitalizing the need for new antimicrobial compounds. A rational approach to dealing with problems of antibiotic resistance requires detailed knowledge of the various biological and non-biological factors that influence the rate and extent of resistance development. A combination therapy combining traditional antibiotics and essential oils is currently blooming and represents a potential area for future investigations. This new generation of phytopharmaceutical may shed light on the development of novel drug regimens in the fight against antibiotic resistance. This review reinforced and described the results of observed synergies between essential oils and antibiotics, and highlighted the potential of essential oils as a potential resistance modifying agent.
The aim of this thesis is to verify whether the bio-reactivity of medicinal oils can be assessed using microorganisms in standard and clinical testing and their sensitivity to specific antibiotics.

The steps of this study can be summarized as follows:
1. The study was conducted on five bacterial samples and one sample of Candida isolated from different medical laboratories.
2. These samples were examined with bacteriology and the samples were cultured under ideal conditions under anaerobic and anaerobic conditions
3. Studying of eight natural essential oils with different antibiotics to, which are onion, garlic, Arugula, rosemary, thyme, parsley, mint and cinnamon, were tested with the following antibiotics, Vancomycin, chloramphenicol, ofloxacin, ampicillin, amoxicillin, , Gentamicin, erythromycin, Fusidic, rifampicin, by well diffusion method used in Egypt to introduce new alternatives against multi-drug.
4. In our study, the parsley oil has antimicrobial activity against the most resistant Klebsiella and E. coli bacteria
5. Identification of most resistant isolates by 16S rRNA confirmed to Candida albicans strain, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus aureus and Streptococcus pyogenes, after doing molecular studies, by studying its genetic sequence, it was registered in the International GenBank.