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Abstract The overall sample was 40 cases; 13 with DMD, 10 with CMD and 17 with RV. The mean age was variable between groups (p-value < 0.001) with the highest in the DMD group (38.3±7.4 years) and the lowest in the CMD group (25.2±4.6 years). The male to female ratio was variable between groups of the study (p-value = 0.03) with the highest ratio 9:4 in the DMD group. There was a significant difference between groups (p < 0.001) regarding dizziness. Regarding history Post-hoc testing revealed that the CMD group (p < 0.001) had less sensation of imbalance or rotation than the two other groups. Asymmetric response of c-VEMP was seen in nine (69.2%) of DMD cases, 14 (82.4%) of RV cases and only in three (30%) of CMD cases, (p-value < 0.001). Low amplitude of o-VEMP was seen in 11 (84.6%) of DMD cases, 9 (90%) of CMD cases, 15 (88.2%) of RV cases, and only in two (25%) of normal cases, (p-value = 0.002). Post-hoc tests for multiple comparisons revealed a significant difference between definitive and cochlear Meniere’s as regard o-VEMP inter-aural amplitude difference (IAD) (p-value = 0.032) only. The duration of symptoms was not significantly different according to laterality of the condition (p = 0.068). There was a significant positive strong correlation between age and ECochG SP/AP ratio, o-VEMP IAD and o-VEMP left ear n1. In addition, there was a significant positive correlation between duration and ECochG SP/AP ratio left ear and between duration and c-VEMP left ear n1. EcochG was more sensitive and more specific than both c-VEMP and o-VEMP in all categories of endolymphatic hydrops. In conclusion, asymmetric response of C-VEMP test can be used as a diagnostic tool in different kinds of Endolymphatic Hydrops (DMD, RV and CMD), but ECochG test was more sensitive and specific. Ocular VEMP is the least sensitive test in the diagnosis of all types of Endolymphatic Hydrops. Cervical VEMP has moderate sensitivity in diagnosis of definitive Meniere’s disease, but low sensitivity in both cochlear Meniere and recurrent vestibulopathy. |