الفهرس 
INTRODUCTION TO CMPAOnly 14 pages are availabe for public view
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Abstract
Objective: to compare the rate of tolerance to whole CMPs (cow’s milk proteins) among infants with confirmed cow’s milk protein allergy (CMPA) allocated to receive partially hydrolyzed formulas (pHF) after 6 months of elimination diet compared to those who continued using Amino-acid based formula (AAF) for 12 months.
Patients and methods: A prospective case controlled clinical trial included 100 infants with confirmed CMPA. They received AAF beside elimination diet for 6 months then were randomly allocated to either group I (50 infants) continued with AAF for another 6 months or group II (50 infants) were shifted gradually to pHF for 6 months. Among group II, infants who did not tolerate pHF were returned back to AFF.
Results: The rate of tolerance to whole CMPs after 12 months of elimination was significantly higher among infants who tolerated pHF after 6 months of elimination (100% of 20 infants) compared to group I (82% of 50 infants). Tolerance to whole CMPs after 12 months was not different between infants who failed the trial of pHF after 6 months (83.3% of 30 infants) compared to group I.
Conclusion: A trial of pHF after 6 months of elimination is beneficial. If tolerated it promotes the final tolerance to whole CMPs with a better taste and at a lower cost compared to AAF whereas it has no detrimental effect on the final tolerance to whole CMPs if not tolerated.