الفهرس 
Introduction and RationaleOnly 14 pages are availabe for public view
 |  | from | 116 |  |  |
| | | from | 116 | | |
Abstract
radiotherapy of head and neck cancer, with a significant impact on the quality of life (QOL) of affected patients, mostly because the long-term effects of the persistence of symptoms/signs during radiotherapy sessions and increased risk of disease recurrence due to interruption of radiotherapy sessions and its treatment remains difficult.
The present study aimed at assessing the efficiency of using glutamine amino acid in decreasing the incidence and severity of chemo-radiotherapy-induced oral mucositis
Accordingly, our case control study included two groups:
o 36 patients were recruited in this study during period of eight months, randomly assigned to either receive glutamine amino acid (study group) or placebo (control group).
o 58.3% of the patients were male and 41.7% were female. The mean age of them was 48.75 ± 8.05.
o 33.3 % of the patients had laryngeal carcinoma, nasopharyngeal carcinoma (27.8%) and carcinoma of oral cavity (25%).
o definitive CCRT regimen was used in (61.1%) in patients ,16% where on adjuvant RT and both adjuvant CCRT and definitive RT were 11%
Oral mucositis (OM) is one of the most severe adverse effects of radiotherapy of head and neck cancer, with a significant impact on the quality of life (QOL) of affected patients, mostly because the long-term effects of the persistence of symptoms/signs during radiotherapy sessions and increased risk of disease recurrence due to interruption of radiotherapy sessions and its treatment remains difficult.
The present study aimed at assessing the efficiency of using glutamine amino acid in decreasing the incidence and severity of chemo-radiotherapy-induced oral mucositis
Accordingly, our case control study included two groups:
o 36 patients were recruited in this study during period of eight months, randomly assigned to either receive glutamine amino acid (study group) or placebo (control group).
o 58.3% of the patients were male and 41.7% were female. The mean age of them was 48.75 ± 8.05.
o 33.3 % of the patients had laryngeal carcinoma, nasopharyngeal carcinoma (27.8%) and carcinoma of oral cavity (25%).
o definitive CCRT regimen was used in (61.1%) in patients ,16% where on adjuvant RT and both adjuvant CCRT and definitive RT were 11%