الفهرس 
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Abstract
This study aimed to evaluate the effect of honey supplementation on plasma levels of short chain fatty acids in healthy infants and on the anthropometric measurements.
The study was single arm prospective interventional study which was conducted on 20 healthy infant. The infants were recruited from Outpatient Pediatric clinic, Ain Shams University Hospitals.
All infants were subjected to:
History taking with special emphasis on the dietetic history, history of any disease that might interfere with the nutrient intake or their metabolism by the body, history of acute or chronic illness.
Clinical examination laying stress on: complete physical examination for each participant before the study, anthropometric measurements before and after honey therapy intervention.
Each infant took oral honey in a dose of 2g/kg/day for 8 weeks, the calculated dose of honey was dissolved in water with a ratio of 1: 3, respectively, and then ingested by the infant before breakfast.
Measurement of serum level of short chain fatty acids (Acetic acid, butyric acid and formic acid levels were estimated at the start of the study and after 8 weeks using HPLC). (Agilent technologies 1100 series, with a quaternary pump (G131A model) according to the method described previously by Miwa & Yamamoto (1987) and modified by Hussein et al. (2014) and Youness et al. (2019).
The studied group was described as regards the sex, age, residency, father and mother education and also frequency of infections and types during honey intervention, also was followed up as regards anthropometric measurements, their Z scores, serum SCFAS level and correlation between serum SCFAS and anthropometric measurements before and after honeysupplementation.
Regarding anthropometric measures, after 2 months of honey supplementation, there was highly statistically significant increase in the Wt, Lt, OFC, mid arm circumference and BMI Z score with p-value = 0.000 and significant increase in weight for length with p- value = 0.017,there was non significant effect on BMI nor WAZ with p- value = 0.323 and 0.190 respectively.
There was also highly statistically significant increase in the Wt with p-value = 0.001 and significant increase in OFC with p- value = 0.037 and non significant effect on Lt with p- value = 0.443 as compared with expected values for age.
In the studied group, there were statistically significant increase in serum level of SCFAS(formic, acetic and butyric with p-value of 0.030, 0.023 and 0.034 respectively).
Regarding correlation between SCFAS level and residency before and after honey intervention, there were no statistically significant effect except for acetic with highly statistical significance increase in urban residents before honey intervention with p-value 0.006.
However there were no statistically significant effect between serum SCFAS level, father and mother education before and after honey intervention correlation.
Regarding correlation between serum SCFAS level and frequency of infections during honey intervention, there were no statistically significant effect with p-value of 0.448,0.343,0.4448 with formic, acetic, butyric respectively.
In the studied group, the results showed that there was no statistically significant correlation between the serum SCFAS level and the anthropometric measurements and their z scores before honey supplementation.
However, they showed that there was highly statistically significant correlation between serum butyric level with Wt, Lt and OFC and serum formic and acetic level with LT with p-value 0.00, while there was statistically significant correlation between serum formic and acetic level with Wt with p-value 0.28 and 0.013 respectively and OFC with p-value0.036 and 0.011 respectively, but there was no significant correlation between serum SCFAS level with BMI, MUAC, Wt for length and their z score after honey supplementation.