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العنوان
Comparative Study between Micro- Needling Alone and Micro- Needling Combined With Platelet-Rich Plasma in the Treatment of Striae Distensae Using Clinical Assessment /
المؤلف
Mohammed, Raghda Sherif.
هيئة الاعداد
باحث / رغدة شريف محمد
مشرف / عبد العزيز عبد السلام احمد
مشرف / عبد العزيز ابراهيم الطويل
الموضوع
Needles. Skin Diseases therapy.
تاريخ النشر
2021.
عدد الصفحات
98 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الأمراض الجلدية
الناشر
تاريخ الإجازة
7/6/2021
مكان الإجازة
جامعة بني سويف - كلية الطب - امراض جلدية وتناسلية
الفهرس
Only 14 pages are availabe for public view

from 122

from 122

Abstract

Summary
Striae distansae or stretch marks are very common, asymptomatic, skin condition frequently seen among females between 5 to 50 years of ages. It often causes cosmetic morbidity and psychological distress, particularly in women and in certain professions where physical appearances have significant importance. Of late, with the increasing emphasis on cosmetic management and awareness, patients approach dermatologists for stretch marks treatment. However, despite several advances, no fully effective treatment has emerged. Unfortunately, there is paucity of the strong evidence in the literature for the effective treatment of striae.
Striae, while otherwise being harmless, are frequent cause of cosmetic concern or disfigurement leading to distress in the affected individuals especially females. With increasing preference for outdoor activities such as gym and swimming; apparels which reveal part of the riff, midriff or thighs, in the modern women, treatment of striae has become a necessity in many patients.
Multiple treatment options have been reported with varying success, from numerous topical to lasers and energy based devices. However, most available publications are small studies, case reports and very few case-controlled double blind trials. Only a few of these are proven and have evidence, whereas many others are hyped by product manufacturers.
Treatment with skin needling might be able to promote the removal of old damaged collagen and induce more collagen growth beneath the epidermis. Puncturing the skin multiple times in acne scars increases the amount of collagen and elastin deposition. Thus, they hypothesized that skin needling would also be useful in striae distensae treatment because they seemed to be dermal scars with epidermal atrophy
The aim of the present study was to compare the safety and efficacy of microneedling alone or in combination with platelet-rich plasma in the treatment of striae distensae.
This was An interventional comparative study was included 30 males and females patients , 16.7% of cases were males, 83.3% of cases were females, mean age was 30.5 ±6.8 years, with range (19-44) years , and carried out at Outpatient Clinic of the Dermatology and Venereology Department, Beni-Suef Hospital. The duration of the study ranged from 6-12 months.
The main results of the study revealed that:
• Male patients represented 16.7% of cases, 83.3% of cases were males, and mean age was 30.5 ±6.8 years, with range (19-44) years.
• Half of the patients had striae distensae due to previous pregnancies, and the other half due to overweight. Stria was abdominal in 46.6%, in the thigh in 26.7%, in the flanks in 26.7% of cases.
• There is no significant difference between the two techniques as regard patient satisfaction.
• There is significant difference between the two techniques as regard Quartile Grading Score.
• There is significant difference between the two groups as regard after treatment clinical score while there is no significant difference between the two techniques as regard before intervention score.
• There is no significant difference between the two techniques as regard post treatment complications.
• There is no significant correlation between degree of improvement Micro- Needling Alone side and age, sex, duration of striae or patient satisfaction.
Based on our findings, we recommend for further studies on large geographical scale and on larger sample size to emphasize our conclusion.