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العنوان
Usage of Doppler-Based Renal resistive index to assess progression of acute kidney injury in septic patients and mortality risk assessment /
المؤلف
Abu El-Fotouh, Islam Ahmed Nour.
هيئة الاعداد
باحث / اسلام أحمد نور أبو الفتوح
مشرف / حمدي محمد صابر
مشرف / خلف ابراهيم الدهيلي
مشرف / أحمد سيد عبد الباسط
الموضوع
Acute renal failure. Renal intensive care. Acute Kidney Injury. Critical Care. Kidney injuries. Kidney Failure, Acute therapy. Kidneys Wounds and injuries.
تاريخ النشر
2021.
عدد الصفحات
132 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب
الناشر
تاريخ الإجازة
15/9/2021
مكان الإجازة
جامعة بني سويف - كلية الطب - حالات حرجة
الفهرس
Only 14 pages are availabe for public view

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from 140

Abstract

Summary
The incidence of AKI in the intensive care unit (ICU) was noted to be 57%, with sepsis being attributed as the etiology in 41% of the cases.
Nowadays Doppler ultrasound is rapidly gaining ground as a screening tool in critically ill patients. The performance of cardiac, lung and abdominal ultrasound in patients after cardiac arrest, major operations and during shock has become standard policy. However, renal ultrasound, which could be easily incorporated in this screening, is not commonly performed.
Our study was an observational cohort study that intended to test the ability of Renal resistive index (RRI) measurement by Doppler Ultra Sound to predict outcome of AKI whether it is transient or persistent in septic patients. And to test the ability of RRI to predict mortality in this group of patients.
This study conducted on 40 patients admitted to critical care department of Beni-Suef university hospital diagnosed as having sepsis and AKI.
Patients were defined as having sepsis according to the definition of the European Society of Intensive Care Medicine.(52) Also patients were definied as having AKI according to KDIGO criteria.(25)
Renal resistive index was measured on ICU admission and 48h from admission.
Our study demonstrated a significant increase of RRI in cases with persistent AKI in comparison to cases with transient AKI (P. value< 0.05).
ROC curve calculation for prediction need of dialysis: cut off value of RRI˃0.64 on admission had the highest area under curve(AUC) (0.959) predicted persistent AKI (P. value< 0.05).
Cut off value of RRI ˃0.64 after 48h had the highest AUC (0.987) predicted persistent AKI (P. value< 0.05).
Also, our study demonstrated a significant increase in APACHE ӀӀӀ score in patients with high RI value (P. < 0.05).
In our study there was significant positive correlation between RI and Lactate level (P.<0.05).
In our study there was significant positive correlation between RI and mean creatinine (P.<0.04).