الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
SUMMARY
Despite of rising incidence of RCC, radical cancer surgery remains the only curative treatment in localized and advanced RCC, therefore pre -operative imaging is most important for the planning of the surgical approach and strategy.
Although US has limitations in providing a complete evaluation of renal tumors before treatment planning, Initial screening and characterization of renal masses and staging of RCCS can benefit from some recent advances of the technique.
One of the most relevant clinical benefits is the early detection of RCCS. US findings strongly suggests the nature of renal tumor with respect to the size and US attenuation characteristics.
MRI diffusion provides a unique insight to tissue cellularity and tissue organization, which is helpful for detecting malignant diseases.
ADC values has been reported to be valuable for quantitively distinguish malignant from benign lesions, In most benign processes, the signal intensity at diffusion-weighted imaging decays with increasing b value, with the result that these benign lesions have high signal intensity on the ADC map, In contrast, slower signal intensity decay or even signal intensity enhancement with increasing b value may indicate malignancy or viable hyper cellular tissue, The degree of restriction of water diffusion in biologic tissue is inversely related to tissue cellularity and the integrity of cell membranes. Consequently, diffusion is most restricted in highly cellular portions of tumors due to reduced extracellular space.
The ADC values of simple and complicated cysts are usually higher than those of solid renal lesions, yet it is not possible to completely distinguish benign from malignant neoplasms on the basis of qualitative assessment of ADC measurement alone.
In our study we aimed to evaluate the role of MRI diffusion to differentiate benign from malignant renal lesions and compare it to US as the first modality of choice.
Our study was conducted on 25 patients of both genders aging from 18 to 65 years old who were recognized to have renal mass lesion by ultrasound.
All patients had US and MRI examination, and then ADC values were calculated. Collected data were subjected to statistical analysis and the following results were obtained:
1) ADC values of benign renal lesions are significantly higher than that of malignant lesions
2) There is useful difference in ADC values of RCC subtypes ADC readings could be more accurate than US, yet US remains the gold standard for early detection of renal masses.