الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Background: Cardiovascular Disease (CVD) and related mortality has emerged as a major health burden worldwide with atherosclerosis being the major cause. Coronary artery disease (CAD) accounts for the major share of the CVD burden Thyroid hormones have more effects on the cardiovascular system, and both hypothyroidism and hyperthyroidism have harmful effects on the heart and vascular system Aim of the work: The aim of this study was to investigate the relationship between serum thyroid stimulating hormone levels (TSH) and the presence and severity of coronary artery disease (CAD) in patients referred for coronary angiography and it`s impact on left ventricular function. Patient and Methods: After taking informed consent, all patients were subjected to the following: Full medical history. Clinical examination. Electrocardiogam. Echocardiography Diagnostic coronary angiography Serum level of TSH Conclusion: Elevated TSH level is associated with presence of coronary artery disease and is correlated with CAD severity by SYNTAX score; but it is not an independent predictor of CAD severity. Elevated TSH level also is associated with LV dysfunction assessed by MPI.